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阿斯巴甜会导致动物体内胰岛素水平上升

2025-03-04 21:39 by 龙岛

低热量甜品到零糖饮料,人工甜味剂一直是满足人们嗜甜欲望的选择。而瑞典卡罗琳斯卡医学院团队近期发表在《细胞代谢》杂志上的新研究揭示,最常用的糖替代品之一——阿斯巴甜可能对血管健康产生负面影响。其会导致动物体内胰岛素水平上升,从而引发动脉粥样硬化,增加炎症反应,并随时间推移提高心脏病和中风的风险。
团队给小鼠连续12周喂食含有0.15%阿斯巴甜的食物,这相当于人类每天饮用约3罐无糖汽水的量。结果显示,相较于未摄入含甜味剂食物的小鼠,这些小鼠动脉中的脂肪斑块更大、更多,同时炎症程度也更高,这些都是心血管健康的负面标志。血液分析表明,阿斯巴甜进入小鼠体内后导致胰岛素水平激增。这是因为身体各处存在的感知甜味的受体在遇到阿斯巴甜时会引导释放更多的胰岛素,而阿斯巴甜比普通糖甜200倍,更能促使这种过度反应。

科技日报:人工甜味剂致动物胰岛素激增

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阿斯巴甜会导致动物体内胰岛素水平上升

2025-03-04 21:39 by 龙岛

低热量甜品到零糖饮料,人工甜味剂一直是满足人们嗜甜欲望的选择。而瑞典卡罗琳斯卡医学院团队近期发表在《细胞代谢》杂志上的新研究揭示,最常用的糖替代品之一——阿斯巴甜可能对血管健康产生负面影响。其会导致动物体内胰岛素水平上升,从而引发动脉粥样硬化,增加炎症反应,并随时间推移提高心脏病和中风的风险。
团队给小鼠连续12周喂食含有0.15%阿斯巴甜的食物,这相当于人类每天饮用约3罐无糖汽水的量。结果显示,相较于未摄入含甜味剂食物的小鼠,这些小鼠动脉中的脂肪斑块更大、更多,同时炎症程度也更高,这些都是心血管健康的负面标志。血液分析表明,阿斯巴甜进入小鼠体内后导致胰岛素水平激增。这是因为身体各处存在的感知甜味的受体在遇到阿斯巴甜时会引导释放更多的胰岛素,而阿斯巴甜比普通糖甜200倍,更能促使这种过度反应。

科技日报:人工甜味剂致动物胰岛素激增

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