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GLP-1RA 的益处和风险

2025-01-26 23:47 by 量子之夜

流行减肥药 GLP-1RA 过去几年风靡世界,华盛顿大学团队分析了美国退伍军人事务部的数据,研究了 215970 名糖尿病患者使用 GLP-1RA 和 175 种健康结果的关系。与使用非 GLP-1RA 抗高血糖药物的对照人群比较后发现,使用 GLP-1RA 的参与者发生凝血和心脏代谢疾病(如深静脉血栓、肺栓塞、中风、心脏骤停、心力衰竭和心肌梗死)的风险较低。他们还提出其他潜在有益效果,包括与较低的精神疾病、癫痫、细菌感染和肺炎风险等相关。同时他们也发现,使用 GLP-1RA 与胃肠道疾病(如恶心呕吐、憩室炎、胃炎和腹痛)以及低血压、晕厥和关节炎风险升高有关。他们强调,该发现是观察性的,不能表明因果关系,但这些发现有助于描述 GLP-1RA 的广泛健康影响。

https://news.sciencenet.cn/htmlnews/2025/1/538137.shtm
https://www.nature.com/articles/s41591-024-03412-w

#医学



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GLP-1RA 的益处和风险

2025-01-26 23:47 by 量子之夜

流行减肥药 GLP-1RA 过去几年风靡世界,华盛顿大学团队分析了美国退伍军人事务部的数据,研究了 215970 名糖尿病患者使用 GLP-1RA 和 175 种健康结果的关系。与使用非 GLP-1RA 抗高血糖药物的对照人群比较后发现,使用 GLP-1RA 的参与者发生凝血和心脏代谢疾病(如深静脉血栓、肺栓塞、中风、心脏骤停、心力衰竭和心肌梗死)的风险较低。他们还提出其他潜在有益效果,包括与较低的精神疾病、癫痫、细菌感染和肺炎风险等相关。同时他们也发现,使用 GLP-1RA 与胃肠道疾病(如恶心呕吐、憩室炎、胃炎和腹痛)以及低血压、晕厥和关节炎风险升高有关。他们强调,该发现是观察性的,不能表明因果关系,但这些发现有助于描述 GLP-1RA 的广泛健康影响。

https://news.sciencenet.cn/htmlnews/2025/1/538137.shtm
https://www.nature.com/articles/s41591-024-03412-w

#医学

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