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科学家可能找到了阻止秃顶的方法

2025-03-30 17:31 by 人猿泰山之密林追踪

治疗秃顶甚至预防秃顶距离我们又近了一步。研究人员发现,负责头发生长的毛囊干细胞 (HFSC) 需要一种起到“保镖”作用的蛋白质 MCL-1。如果 MCL-1 因为压力、衰老、抗癌药物或遗传等降低水平,HSFC 会逐渐筋疲力尽最终走向死亡,也就不会长出新头发了。研究人员通过关闭生成 MCL-1 蛋白质的基因并剔除实验鼠的现有毛发演示了其作用。他们发现 HFSC 存活了一段时间,但最终因为触发压力信号 (P53)而走向死亡。研究报告发表在《Nature Communications》期刊上。最新发现为治疗和预防脱发开辟了新的研究方向。

Nature Communications:MCL‑1 safeguards activated hair follicle stem cells to enable adult hair regeneration

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科学家可能找到了阻止秃顶的方法

2025-03-30 17:31 by 人猿泰山之密林追踪

治疗秃顶甚至预防秃顶距离我们又近了一步。研究人员发现,负责头发生长的毛囊干细胞 (HFSC) 需要一种起到“保镖”作用的蛋白质 MCL-1。如果 MCL-1 因为压力、衰老、抗癌药物或遗传等降低水平,HSFC 会逐渐筋疲力尽最终走向死亡,也就不会长出新头发了。研究人员通过关闭生成 MCL-1 蛋白质的基因并剔除实验鼠的现有毛发演示了其作用。他们发现 HFSC 存活了一段时间,但最终因为触发压力信号 (P53)而走向死亡。研究报告发表在《Nature Communications》期刊上。最新发现为治疗和预防脱发开辟了新的研究方向。

Nature Communications:MCL‑1 safeguards activated hair follicle stem cells to enable adult hair regeneration

#科学

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